parietal cell การใช้
- This creates a diffuse from the cytoplasm into the parietal cell canaliculi.
- Mucous neck cells are located within gastric glands, interspersed between parietal cells.
- The parietal cells secrete hydrochloric acid the main component of gastric acid.
- A big meal also kicks the parietal cells into overdrive, producing more acid.
- This is the major stimulus for acid secretion by parietal cells.
- Another important secretion of the parietal cells is intrinsic factor.
- The vagus normally stimulates the stomach's parietal cells to secrete acid and intrinsic factor.
- All three of these stimulate parietal cells to secrete hydrochloric acid and intrinsic factor.
- The pylorus also contains scattered parietal cells and neuroendocrine cells.
- Once present, acetylcholine activates G cells and parietal cells.
- Histamine also stimulates H + secretion from parietal cells.
- The presence of serum antibodies to parietal cells and to intrinsic factor are characteristic findings.
- Parietal cells contain an extensive secretory network ( called H + / K + ATPase.
- Gastrin acts on parietal cells directly and indirectly too, by stimulating the release of histamine.
- However the decrease in pH caused by activation of parietal cells further activates gastric chief cells.
- One, the parietal cells in the body of the stomach are stimulated to release H +.
- KCNE2 is also highly expressed in parietal cells of the gastric epithelium, also at the apical side.
- Intrinsic factor antibodies are much less sensitive than parietal cell antibodies, but they are much more specific.
- Chloride and hydrogen ions are secreted separately from the cytoplasm of parietal cells and mixed in the canaliculi.
- KCNE2 protein is most readily detected in the choroid plexus epithelium, gastric parietal cells, and thyroid epithelial cells.
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